Thirst is the the craving that vampires have when they need blood. Vampires need blood to survive because of the vampire virus. The virus constantly burns their hemoglobin, so they feed on others blood for sustanence and to replemish their hemoglobin. If a vampire goes a prolonged time without blood, in Blade's case serum, the vampire has some symptoms of heroin withdrawl, extreme weakness and fatigue.

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